1. Women with positive urine pregnancy test, women who are pregnant, breastfeeding, or women who plan to become pregnant within 6 months, 2. Suffering from a serious chronic disease or the disease is in a progressive stage and cannot be controlled smoothly, such as diabetes, asthma, thyroid disease, etc. that cannot be controlled by drugs, 3. Suffering from thrombocytopenia, bleeding disorders or thrombotic disorders, 4. Suffering from more serious cardiovascular diseases, such as arrhythmia, conduction block, myocardial infarction, severe hypertension that cannot be controlled by drugs, etc., 5. Suffering from congenital or acquired angioedema/neurotic edema, 6. History or family history of convulsions, epilepsy, encephalopathy, other progressive neurological diseases and psychiatric diseases, 7. Suffering from lymphoma, leukemia and other systemic malignant tumors, 8. Suffering from autoimmune diseases, 9. Those with fainting needles, 10. Has received immunosuppressive therapy, antiallergic therapy, cytotoxic therapy, or inhaled corticosteroids in the past 6 months (excluding corticosteroid spray therapy for allergic rhinitis, and surface corticosteroid therapy for acute non-complicated dermatitis), 11. Received blood products within 4 months before receiving the experimental vaccine, 12. Received other research drugs within 1 month before receiving the experimental vaccine, 13. Receive other types of vaccines within 1 month before receiving the experimental vaccine, 14. Patients with acute exacerbation of chronic diseases or acute infectious diseases and fever.

1. Women with positive urine pregnancy test, women who are pregnant, breastfeeding, or women who plan to become pregnant within 6 months, 2. Suffering from a serious chronic disease or the disease is in a progressive stage and cannot be controlled smoothly, such as diabetes, asthma, thyroid disease, etc. that cannot be controlled by drugs, 3. Suffering from thrombocytopenia, bleeding disorders or thrombotic disorders, 4. Suffering from more serious cardiovascular diseases, such as arrhythmia, conduction block, myocardial infarction, severe hypertension that cannot be controlled by drugs, etc., 5. Suffering from congenital or acquired angioedema/neurotic edema, 6. History or family history of convulsions, epilepsy, encephalopathy, other progressive neurological diseases and psychiatric diseases, 7. Suffering from lymphoma, leukemia and other systemic malignant tumors, 8. Suffering from autoimmune diseases, 9. Those with fainting needles, 10. Has received immunosuppressive therapy, antiallergic therapy, cytotoxic therapy, or inhaled corticosteroids in the past 6 months (excluding corticosteroid spray therapy for allergic rhinitis, and surface corticosteroid therapy for acute non-complicated dermatitis), 11. Received blood products within 4 months before receiving the experimental vaccine, 12. Received other research drugs within 1 month before receiving the experimental vaccine, 13. Receive other types of vaccines within 1 month before receiving the experimental vaccine, 14. Patients with acute exacerbation of chronic diseases or acute infectious diseases and fever.

1. Women with positive urine pregnancy test, pregnant, lactating women, or women with pregnancy plan within 6 months, 2. severe chronic disease or disease can not be controlled smoothly during the progress, such as diabetes, asthma, thyroid disease, which can not be controlled by drugs, 3. Suffering from thrombocytopenia, hemorrhagic disease or thrombotic disease, 4. Suffer from more serious cardiovascular diseases, such as arrhythmia, conduction block, myocardial infarction, severe hypertension and uncontrollable drugs, 5. Have congenital or acquired angioedema / neuroedema, 6. History or family history of convulsion, epilepsy, encephalopathy, other progressive nervous system diseases and mental diseases, 7. Suffering from lymphoma, leukemia and other systemic malignancies, 8. Suffering from autoimmune diseases, 9. Needle fainter, 10. in the past 6 months, there have been immunosuppressive therapy, antiallergic therapy, cytotoxic therapy, inhalation of corticosteroids (excluding corticosteroid spray therapy for allergic rhinitis, and acute corticosteroid therapy without dermatitis), 11. Blood products were received within 4 months before receiving the test vaccine, 12. Other study drugs were received within 1 month before receiving the trial vaccine, 13. Receive other vaccines within 1 month before receiving the test vaccine, 14. Acute attack of chronic diseases or acute infectious diseases and fever.

1. Women with positive urine pregnancy test, pregnant, lactating women, or women with pregnancy plan within 6 months, 2. severe chronic disease or disease can not be controlled smoothly during the progress, such as diabetes, asthma, thyroid disease, which can not be controlled by drugs, 3. Suffering from thrombocytopenia, hemorrhagic disease or thrombotic disease, 4. Suffer from more serious cardiovascular diseases, such as arrhythmia, conduction block, myocardial infarction, severe hypertension and uncontrollable drugs, 5. Have congenital or acquired angioedema / neuroedema, 6. History or family history of convulsion, epilepsy, encephalopathy, other progressive nervous system diseases and mental diseases, 7. Suffering from lymphoma, leukemia and other systemic malignancies, 8. Suffering from autoimmune diseases, 9. Needle fainter, 10. in the past 6 months, there have been immunosuppressive therapy, antiallergic therapy, cytotoxic therapy, inhalation of corticosteroids (excluding corticosteroid spray therapy for allergic rhinitis, and acute corticosteroid therapy without dermatitis), 11. Blood products were received within 4 months before receiving the test vaccine, 12. Other study drugs were received within 1 month before receiving the trial vaccine, 13. Receive other vaccines within 1 month before receiving the test vaccine, 14. Acute attack of chronic diseases or acute infectious diseases and fever.