1.-Quantification of specific anti-RBD IgG antibody titers (AU / mL). Measurement time: at 14 days after the administration of the dose with respect to the baseline.2.-Percentage (%) of inhibition of the binding of the RBD protein to the ACE2 receptor in serum. Measurement time: on days 14 and 28 after the administration of the dose; and every 28 days until the decrease in titers.

1.-Quantification of specific anti-RBD IgG antibody titers (AU / mL). Measurement time: at 14 days after the administration of the dose with respect to the baseline.2.-Percentage (%) of inhibition of the binding of the RBD protein to the ACE2 receptor in serum. Measurement time: on days 14 and 28 after the administration of the dose; and every 28 days until the decrease in titers.