Created at Source Raw Value Validated value
July 7, 2022, 1:30 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Immunogenicity; Vaccine;Immunotherapy; Active;Vaccination;Single Dose ;Injections; Intramuscular;Administration; Intranasal;Nasal Sprays;Instillation; Drug ;CIGB-669; \r CIGB-66; \r MAMBISA; \r ABDALA;Stage IGroup A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "spray by nasal route, 1 shot in each nostril", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "nasal route, 2 drops in each nostril", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "Stage II ", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "Stage II intramuscular", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}]

June 23, 2022, 2 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Stage IGroup A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).;Immunogenicity; Vaccine;Immunotherapy; Active;Vaccination;Single Dose ;Injections; Intramuscular;Administration; Intranasal;Nasal Sprays;Instillation; Drug ;CIGB-669; \r CIGB-66; \r MAMBISA; \r ABDALA", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).;Immunogenicity; Vaccine;Immunotherapy; Active;Vaccination;Single Dose ;Injections; Intramuscular;Administration; Intranasal;Nasal Sprays;Instillation; Drug ;CIGB-669; \r CIGB-66; \r MAMBISA; \r ABDALA", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "spray by nasal route, 1 shot in each nostril, single dose (Mambisa group)", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "drops by nasal route, 2 drops in each nostril, single dose (Mambisa group)", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "Cuban prototype spray by nasal route, 1 shot in each nostril, single dose (Mambisa group)", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "by intramuscular route, in the deltoid region, single dose (Abdala group)", "treatment_id": 1975, "treatment_name": "Cigb-66", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "Stage II Mambisa Group: of the variant selected by nasal route, single dose (Mambisa group)", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "", "treatment_id": 1975, "treatment_name": "Cigb-66", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}]

June 17, 2022, 12:30 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Immunogenicity; Vaccine;Immunotherapy; Active;Vaccination;Single Dose ;Injections; Intramuscular;Administration; Intranasal;Nasal Sprays;Instillation; Drug ;CIGB-669; \r CIGB-66; \r MAMBISA; \r ABDALA;Stage IGroup A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "by nasal route, 1 shot in each nostril, single dose", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "by nasal route, 2 drops in each nostril, single dose", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "the variant selected by nasal route, single dose", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "by intramuscular route, in the deltoid region, single dose", "treatment_id": 1975, "treatment_name": "Cigb-66", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}]

July 16, 2021, 2 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Stage IGroup A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).;Immunogenicity; Vaccine;Immunotherapy; Active;Vaccination;Single Dose ;Injections; Intramuscular;Administration; Intranasal;Nasal Sprays;Instillation; Drug ;CIGB-669; \n CIGB-66; \n MAMBISA; \n ABDALA", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group A: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group B: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L drops by nasal route; 2 drops in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group C: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L Cuban prototype spray by nasal route; 1 shot in each nostril; single dose (Mambisa group).", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).Stage IIMambisa Group: Vaccine candidate CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L of the variant selected by nasal route; single dose (Mambisa group).Abdala Group D: Vaccine candidate CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0;30 mg)/0;5 mL by intramuscular route; in the deltoid region; single dose (Abdala group).;Immunogenicity; Vaccine;Immunotherapy; Active;Vaccination;Single Dose ;Injections; Intramuscular;Administration; Intranasal;Nasal Sprays;Instillation; Drug ;CIGB-669; \n CIGB-66; \n MAMBISA; \n ABDALA", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L;1;Nose (spray)\n", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L;1;Nose (drop)\n", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "CIGB-669 (RBD 50 \u00b5g + 40 \u00b5g de HBcAg)/200 \u00b5L;1;Nose (Cuban prototype spray)\n", "treatment_id": 1976, "treatment_name": "Cigb-669", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "CIGB-66 (RBD 50 \u00b5g + Aluminum hydroxide 0,30 mg)/0,5 mL;1;IM\n", "treatment_id": 1975, "treatment_name": "Cigb-66", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}]