Created at Source Raw Value Validated value
Dec. 10, 2021, 2 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "30 patients will be included; divided into two groups: 15 volunteers will be included in the Electrostimulation Group and 15 volunteers will be included in the Placebo group; that is; with the device turned off. The motor points of the muscles: biceps brachii (BB); vastus lateralis (VL); vastus medialis (VM); hamstrings (IT); triceps surae (TS) and tibialis anterior (TA) will be located prior to stimulation. A pen will be used to apply the current; with a stimulus area of ??1 cm\u00b2; in order to locate the best contractile response point. The intensity will be fixed; square pulse; biphasic; balanced and increasing width; from 0ms to 500ms. The Electrodiagnostic Test consists of a sequence of transcutaneous electrical stimuli to detect electrophysiological and neuromuscular changes. The Reobase; Chronaxia and Accommodation will be checked at the previously located motor points. Rheobase is the lowest intensity of a square; biphasic; balanced pulse whose action potential is sufficient to generate visible muscle contraction. The chronaxia is the smallest square; biphasic; balanced pulse width; which at twice the intensity of the rheobase can generate visible muscle contraction. Accommodation is the lowest pulse intensity with a slow; exponential rise that generates muscle contraction. The TEDE will be performed at three times: on admission of the patient to the ICU; after 24 hours of mechanical ventilation and after 14 days of NMES.Ultrasonography with a linear head; frequency of 7.5 megaHz and depth of 4-6 cm will be used to assess the thickness and angle of skeletal muscle fibers. The probe will be positioned transversely; in the craniocaudal direction; without excessive compression force. The patient will be in supine position; with the lower limbs in extension. Ul;V02.734;E02.760.169.063.500", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 879, "treatment_name": "Neuromuscular electrical stimulation", "treatment_type": "Medical device", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]