Created at Source Raw Value Validated value
Dec. 10, 2021, 2 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "The treatment will be carried out during the hospitalization of patients at Lydia Storopoli Hospital. A physiotherapist will go to the patient's bedside and position the non-invasive vagus nerve stimulation equipment or sham.Non-invasive vagus nerve stimulationNon-invasive stimulation of the vagus nerve will be performed in 10 patients diagnosed with Covid-19; using a multifunctional transcutaneous electrical neuromuscular stimulator; model Dualpex 071 from Quark Produtos M\u00e9dicos. The round; flexible electrostimulation adhesive electrodes; size 15mm; will be placed over the tragus on the left side; with alternating current ranging from 25 Hz to 5 kHz per series of sine waves; with a pulse width of 1 ms; for 90 minutes and adjusted intensity between 0.5 mA and 12 mA based on the patient's tolerance; which does not cause pain or muscle contraction. Stimulations take place twice a day (morning and afternoon / evening with an interval of 8 to 10 hours between each session); for 7 consecutive days.Sham InterventionSham intervention will be performed in 10 defined with a diagnosis of Covid-19. For Sham stimulation; a multifunctional transcutaneous neuromuscular electrical stimulator; model Dualpex 071 of the Quark Medical Products brand; will be used. Round flexible adhesive electrodes; size 15mm; will be placed over the tragus on the left side; however the device will not be turned on. But it will be kept in place for 90 minutes. Sham stimulations occur twice a day (morning and afternoon / evening with an interval of 8 to 10 hours between each session); for 7 consecutive days.Vagus nerve stimulation participations will be performed if authorized by the physician (or medical team) responsible for the day and period; in order not to increase t;E02.331.900", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 903, "treatment_name": "Non-invasive vagus nerve stimulator", "treatment_type": "Medical device", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]