1. Agree to sign the study informed consent form (ICF) before performing any study-specific procedure. 2. Adults = 18 years old 3. Absence of COVID-19 that is confirmed with negative immunochromatographic SARS-CoV-2 antigen rapid test at randomization test use of point of care test system at the screening visit 4. Consent for using effective methods of contraception during the entire trial and 3 months after its completion 5. No evidence of pronounced vaccine-induced reactions or complications after receiving immunobiological products in medical history. 6. No acute infectious and/or respiratory diseases within at least 14 days before the enrollment.

1. Agree to sign the study informed consent form (ICF) before performing any study-specific procedure. 2. Adults = 18 years old 3. Absence of COVID-19 that is confirmed with negative immunochromatographic SARS-CoV-2 antigen rapid test at randomization test use of point of care test system at the screening visit 4. Consent for using effective methods of contraception during the entire trial and 3 months after its completion 5. No evidence of pronounced vaccine-induced reactions or complications after receiving immunobiological products in medical history. 6. No acute infectious and/or respiratory diseases within at least 14 days before the enrollment.