Patients who fall into any of the following criteria are excluded from participating in the study:1. Patients who has the symptom 8 days or longer.2. Patients who are treated by macrolide antimicrobial agents. 3. Patients who are treated by steroids (except inhalants) or immunosuppressive agents4. Patients who are diagnosed with influenza.5. Patients whose SPO2 is less than or equal to 93%. (at room)6. Patients with hepatic dysfunction. (AST / ALT more than 5 times of the facility standard value or Child-Pugh B/C)7. Patients with renal dysfunction. (Cre more than twice of the facility standard value and eGFR<30ml/min)8. Patients whose peripheral blood neutrophils are less than 1,000/uL.9. Patients who have history of hypersensitivity to macrolide antimicrobial agents.10. Patients who are pregnant, breastfeeding.11. Patients who have been vaccinated against COVID-19 in the past.12. Patients with other conditions that the investigator thinks inappropriate to participate in the study.

Patients who fall into any of the following criteria are excluded from participating in the study:1. Patients who has the symptom 8 days or longer.2. Patients who are treated by macrolide antimicrobial agents. 3. Patients who are treated by steroids (except inhalants) or immunosuppressive agents4. Patients who are diagnosed with influenza.5. Patients whose SPO2 is less than or equal to 93%. (at room)6. Patients with hepatic dysfunction. (AST / ALT more than 5 times of the facility standard value or Child-Pugh B/C)7. Patients with renal dysfunction. (Cre more than twice of the facility standard value and eGFR<30ml/min)8. Patients whose peripheral blood neutrophils are less than 1,000/uL.9. Patients who have history of hypersensitivity to macrolide antimicrobial agents.10. Patients who are pregnant, breastfeeding.11. Patients who have been vaccinated against COVID-19 in the past.12. Patients with other conditions that the investigator thinks inappropriate to participate in the study.

Patients who fall into any of the following criteria are excluded from participating in the study:1. Patients who has the symptom 8 days or longer.2. Patients who are treated by macrolide antimicrobial agents. 3. Patients who are treated by steroids (except inhalants) or immunosuppressive agents4. Patients who are diagnosed with influenza.5. Patients whose SPO2 is less than or equal to 94%. (at room)6. Patients with hepatic dysfunction. (AST / ALT more than 5 times of the facility standard value or Child-Pugh B/C)7. Patients with renal dysfunction. (Cre more than twice of the facility standard value and eGFR<30ml/min)8. Patients whose peripheral blood neutrophils are less than 1,000/uL.9. Patients who have history of hypersensitivity to macrolide antimicrobial agents.10. Patients who are pregnant, breastfeeding.11. Patients who have been vaccinated against COVID-19 in the past.12. Patients with other conditions that the investigator thinks inappropriate to participate in the study.

Patients who fall into any of the following criteria are excluded from participating in the study:1. Patients who has the symptom 8 days or longer.2. Patients who are treated by macrolide antimicrobial agents. 3. Patients who are treated by steroids (except inhalants) or immunosuppressive agents4. Patients who are diagnosed with influenza.5. Patients whose SPO2 is less than or equal to 94%. (at room)6. Patients with hepatic dysfunction. (AST / ALT more than 5 times of the facility standard value or Child-Pugh B/C)7. Patients with renal dysfunction. (Cre more than twice of the facility standard value and eGFR<30ml/min)8. Patients whose peripheral blood neutrophils are less than 1,000/uL.9. Patients who have history of hypersensitivity to macrolide antimicrobial agents.10. Patients who are pregnant, breastfeeding.11. Patients who have been vaccinated against COVID-19 in the past.12. Patients with other conditions that the investigator thinks inappropriate to participate in the study.