Created at Source Raw Value Validated value
April 23, 2021, 12:45 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Method of randomization: block randomization (blocks of 6 and 12 in the general cohort; blocks of 6 in the immunology cohort). ChAdOx1-nCoV-19 groups (n = 525) (participants who had their prime dose of this vaccine through the national rollout) will be split into two groups: 1. Immunology group (n = 75) - heterologous boost with either COVID-19 Vaccine Moderna (n = 25); Novavax; NXM-CoV2373 (n = 25); or homologous boost (n = 25); at Day 56-84 post prime. Follow up at days 7; 14; 28; 56; 112; 294 post-boost. 2. General group (n = 450) - heterologous boost with either COVID-19 Vaccine Moderna (n = 150); Novavax; NXM-CoV2373 (n = 150); or homologous boost (n = 150); at Day 56-84 post prime. Follow up at days 28; 56; 112; 294 post-boost. BNT162b2 groups (n = 525) (participants who had their prime dose of this vaccine through the national rollout) will be split into two groups: 1. Immunology group (n = 75) - heterologous boost with either COVID-19 Vaccine Moderna (n = 25); Novavax; NXM-CoV2373 (n = 25); or homologous boost (n = 25); at Day 56-84 post prime. Follow up at days 7; 14; 28; 56; 112; 294 post-boost. 2. General group (n = 450) - heterologous boost with either COVID-19 Vaccine Moderna (n = 150); Novavax; NXM-CoV2373 (n = 150); or homologous boost (n = 150); at Day 56-84 post prime. Follow up at days 28; 56; 112; 294 post-boost.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "1. Immunology group (n = 75) - heterologous boost with either COVID-19 Vaccine Moderna (n = 25); Novavax; NXM-CoV2373 (n = 25); or homologous boost (n = 25); at Day 56-84 post prime. Follow up at days 7; 14; 28; 56; 112; 294 post-boost.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "1. Immunology group (n = 75) - heterologous boost with either COVID-19 Vaccine Moderna (n = 25); Novavax; NXM-CoV2373 (n = 25); or homologous boost (n = 25); at Day 56-84 post prime. Follow up at days 7; 14; 28; 56; 112; 294 post-boost.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "2. General group (n = 450) - heterologous boost with either COVID-19 Vaccine Moderna (n = 150); Novavax; NXM-CoV2373 (n = 150); or homologous boost (n = 150); at Day 56-84 post prime. Follow up at days 28; 56; 112; 294 post-boost.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "2. General group (n = 450) - heterologous boost with either COVID-19 Vaccine Moderna (n = 150); Novavax; NXM-CoV2373 (n = 150); or homologous boost (n = 150); at Day 56-84 post prime. Follow up at days 28; 56; 112; 294 post-boost.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "heterologous boost mRNA-1273 at day56 to 84;1 (ChAdOx1-nCoV-19 prime group)", "treatment_id": 824, "treatment_name": "Mrna-1273", "treatment_type": "Rna based vaccine", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "heterologous boost NVX-CoV2373 at day56 to 84;1 (ChAdOx1-nCoV-19 prime group)", "treatment_id": 918, "treatment_name": "Nvx-cov2373", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "homologous boost at day56 to 84;1 (ChAdOx1-nCoV-19 prime group)", "treatment_id": 161, "treatment_name": "Chadox1 ncov-19", "treatment_type": "Non replicating viral vector", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "heterologous boost mRNA-1273 at day56 to 84;1 (BNT162b2 prime group)", "treatment_id": 824, "treatment_name": "Mrna-1273", "treatment_type": "Rna based vaccine", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "heterologous boost NVX-CoV2373 at day56 to 84;1 (BNT162b2 prime group)", "treatment_id": 918, "treatment_name": "Nvx-cov2373", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "homologous boost at day56 to 84;1 (BNT162b2 prime group)", "treatment_id": 222, "treatment_name": "Bnt162b2", "treatment_type": "Rna based vaccine", "pharmacological_treatment": "Vaccine"}]