1. Male and female subjects aged 18 to 45 years, inclusive, 2. The body weight no less than 50 kg for male subjects and no less than 45 kg for female subjects. Body mass index (BMI) = weight (kg)/square of height (m2), ranging from 18-28 kg/m2 (including the critical value), 3. These indicators are normal including physical examination, vital signs, laboratory tests and other accessory examinations (chest radiology, abdominal B-mode ultrasonography, ECG, etc.), or above indicators are aberrant but clinically insignificant, 4. No plan of pregnancy and being willing to use effective contraceptive measures for subject (including partner) from informed consent to 6 months after administration of investigational product, see Appendix 5 for the specific contraceptive measures, 5. The subjects are able to understand the content of the study and voluntary to sign the informed consent form, meanwhile, being able to complete the study as required in the protocol.

1. Male and female subjects aged 18 to 45 years, inclusive, 2. The body weight no less than 50 kg for male subjects and no less than 45 kg for female subjects. Body mass index (BMI) = weight (kg)/square of height (m2), ranging from 18-28 kg/m2 (including the critical value), 3. These indicators are normal including physical examination, vital signs, laboratory tests and other accessory examinations (chest radiology, abdominal B-mode ultrasonography, ECG, etc.), or above indicators are aberrant but clinically insignificant, 4. No plan of pregnancy and being willing to use effective contraceptive measures for subject (including partner) from informed consent to 6 months after administration of investigational product, see Appendix 5 for the specific contraceptive measures, 5. The subjects are able to understand the content of the study and voluntary to sign the informed consent form, meanwhile, being able to complete the study as required in the protocol.