1. Signed informed consent prior to any study-mandated procedure,2. Male or female subjects, 18 to 70 years of age, inclusive at screening,3. Body mass index (BMI) between 18 and 32 kg/m2, inclusive at screening, and with a minimum weight of 50 kg.4. Participant must be healthy, in the investigator’s clinical judgment, as confirmed by medical history, physical examination, vital signs, ECG and laboratory assessments performed at screening,5. Willing to comply with effective contraception during the study if subject is male or women of child bearing potential, up to 90 days after the last dose of study treatment.6. Has the ability to communicate well with the investigator in the Dutch language and willing to comply with the study restrictions

1. Signed informed consent prior to any study-mandated procedure,2. Male or female subjects, 18 to 70 years of age, inclusive at screening,3. Body mass index (BMI) between 18 and 32 kg/m2, inclusive at screening, and with a minimum weight of 50 kg.4. Participant must be healthy, in the investigator’s clinical judgment, as confirmed by medical history, physical examination, vital signs, ECG and laboratory assessments performed at screening,5. Willing to comply with effective contraception during the study if subject is male or women of child bearing potential, up to 90 days after the last dose of study treatment.6. Has the ability to communicate well with the investigator in the Dutch language and willing to comply with the study restrictions