inclusion criteria: * patients with pcr positive for sars-cov-2 * hospitalized with moderate to severe respiratory symptoms as assessed by the egyptian ministry of health national guidelines * informed consent explained \& signed by patient or his 1st degree relatives or legally authorized representative.

inclusion criteria: * patients with pcr positive for sars-cov-2 * hospitalized with moderate to severe respiratory symptoms as assessed by the egyptian ministry of health national guidelines * informed consent explained \& signed by patient or his 1st degree relatives or legally authorized representative.

inclusion criteria: - patients with pcr positive for sars-cov-2 - hospitalized with moderate to severe respiratory symptoms as assessed by the egyptian ministry of health national guidelines - informed consent explained & signed by patient or his 1st degree relatives or legally authorized representative.

inclusion criteria: - patients with pcr positive for sars-cov-2 - hospitalized with moderate to severe respiratory symptoms as assessed by the egyptian ministry of health national guidelines - informed consent explained & signed by patient or his 1st degree relatives or legally authorized representative.