- Nature; frequency and severity of local reactions. Solicited adverse events include: pain; redness and swelling at the injection site and pain and swelling at the regional lymph nodes- Nature; frequency and severity of systemic events. Solicited adverse events include: fever; fatigue; headache; chills; vomiting; diarrhea; new or worsened muscle pain; and new or worsened joint pain.- Use of antipyretics and painkillers- SARS-CoV-2 WT neutralizing antibody titers rate on Day 43- SARS-CoV-2-spike protein–specific binding IgG level on D 43

- Nature; frequency and severity of local reactions. Solicited adverse events include: pain; redness and swelling at the injection site and pain and swelling at the regional lymph nodes- Nature; frequency and severity of systemic events. Solicited adverse events include: fever; fatigue; headache; chills; vomiting; diarrhea; new or worsened muscle pain; and new or worsened joint pain.- Use of antipyretics and painkillers- SARS-CoV-2 WT neutralizing antibody titers rate on Day 43- SARS-CoV-2-spike protein–specific binding IgG level on D 43