Name: Clinical improvement was defined as improvement of at least two points from the baseline from date of intervention administration until the date of discharge from hospital or date of death from any cause; whichever came first; assessed up to 1-month status on the six-category ordinal scale. This scale contains the subsequent categories: (1) death (2) hospital admission requiring invasive mechanical ventilation (3) hospital admission; requiring non-invasive positive pressure ventilation (4) hospital admission; requiring oxygen (5) hospital admission; not requiring oxygen (6) discharge.;Timepoints: we will follow our patients for a total of 28 days . ;Measure: Clinical Improvement

Name: Clinical improvement was defined as improvement of at least two points from the baseline from date of intervention administration until the date of discharge from hospital or date of death from any cause; whichever came first; assessed up to 1-month status on the six-category ordinal scale. This scale contains the subsequent categories: (1) death (2) hospital admission requiring invasive mechanical ventilation (3) hospital admission; requiring non-invasive positive pressure ventilation (4) hospital admission; requiring oxygen (5) hospital admission; not requiring oxygen (6) discharge.;Timepoints: we will follow our patients for a total of 28 days . ;Measure: Clinical Improvement