The participant is known to be hypersensitive to the studied drug (heparin) or to chemically related compounds. History of serious adverse reactions or hypersensitivity to any drug. The participant has any condition that prevents him from participating in the study due to the investigator's judgment. A participant shows a positive result for beta-HCG test and/or urine test for pregnancy, delivery or abortion in the 12 weeks prior to the scheduled vaccine administration date. Present COPD.

The participant is known to be hypersensitive to the studied drug (heparin) or to chemically related compounds. History of serious adverse reactions or hypersensitivity to any drug. The participant has any condition that prevents him from participating in the study due to the investigator's judgment. A participant shows a positive result for beta-HCG test and/or urine test for pregnancy, delivery or abortion in the 12 weeks prior to the scheduled vaccine administration date. Present COPD.