1. Weight outside range 50 kg – 120 kg (110 lbs – 265 lbs). 2. Self-reported or laboratory confirmed previous or current diagnosis of SARS-CoV-2. 3. Self-reported current acute respiratory infection. 4. Concurrent and/or recent use of the investigational product, a product considered to be equivalent to the investigational product, or any other product that is likely to interfere with the investigational products in this trial or the interpretation of trial data . 5. Self-reported known allergies to any of the IMPs and excipients of the IMPs and placebo. 6. Self-reported presence or history of the conditions listed in the appendices. 7. Self-reported current use of medication with known to interact with any of the medications listed in the appendices. 8. Inability or unwillingness to be followed up for the trial period

1. Weight outside range 50 kg – 120 kg (110 lbs – 265 lbs). 2. Self-reported or laboratory confirmed previous or current diagnosis of SARS-CoV-2. 3. Self-reported current acute respiratory infection. 4. Concurrent and/or recent use of the investigational product, a product considered to be equivalent to the investigational product, or any other product that is likely to interfere with the investigational products in this trial or the interpretation of trial data . 5. Self-reported known allergies to any of the IMPs and excipients of the IMPs and placebo. 6. Self-reported presence or history of the conditions listed in the appendices. 7. Self-reported current use of medication with known to interact with any of the medications listed in the appendices. 8. Inability or unwillingness to be followed up for the trial period