Created at Source Raw Value Validated value
Jan. 30, 2021, 12:45 a.m. oms

1. Subjects with history of severe infections (pneumonia, septicemia, etc.), severe cardiac or pulmonary diseases, or received immunosuppressive therapy or other investigational drugs within the previous 30 days of screening 2. Known or suspected hypersensitivity to Artemisinin 3. Women of child bearing potential who are currently pregnant, lactating or who are not willing to use contraception during the entire duration of the study 4. Men who are unwilling to use contraception while receiving investigational product 5. Subjects with history of severe disease other than COVID-19 which is expected to prevent compliance with the present protocol 6. Subjects with history of severe renal and hepatic impairment. (creatine =2 mg/dl, liver enzymes and bilirubin 2.5 times ULN,alkaline phosphatase 1.5 times ULN) 7. Recent treatment with Artemisinin or Artemisinin based antimalarials in the past 7 days 8. Known history of failure to control systemic fungal, bacterial or viral infection 9. Patients with the following co-morbidities: insulin-dependent diabetes, hypertension with cardiac symptoms, morbid obesity with diabetes and/or hypertension 10. Subjects with known human immunodeficiency virus (HIV) or hepatitis B or C classes of active viral infection 11. Have a history of neurological or psychiatric disorders, including epilepsy or dementia 12. Subjects for whom ventilator support is required at screening 13. Patients not willing to stay in hospital for 5 days of isolation following diagnosis of Covid-19 14. Subjects not willing to give their informed consent to participate in the clinical trial Subjects having uncontrolled diabetes, uncontrolled hypertension. 16. According to the investigator's judgment, there are concomitant diseases with a serious safety hazard or affect the subject 17. Using other experimental drugs or participating in other clinical trials in the prior one month.

1. Subjects with history of severe infections (pneumonia, septicemia, etc.), severe cardiac or pulmonary diseases, or received immunosuppressive therapy or other investigational drugs within the previous 30 days of screening 2. Known or suspected hypersensitivity to Artemisinin 3. Women of child bearing potential who are currently pregnant, lactating or who are not willing to use contraception during the entire duration of the study 4. Men who are unwilling to use contraception while receiving investigational product 5. Subjects with history of severe disease other than COVID-19 which is expected to prevent compliance with the present protocol 6. Subjects with history of severe renal and hepatic impairment. (creatine =2 mg/dl, liver enzymes and bilirubin 2.5 times ULN,alkaline phosphatase 1.5 times ULN) 7. Recent treatment with Artemisinin or Artemisinin based antimalarials in the past 7 days 8. Known history of failure to control systemic fungal, bacterial or viral infection 9. Patients with the following co-morbidities: insulin-dependent diabetes, hypertension with cardiac symptoms, morbid obesity with diabetes and/or hypertension 10. Subjects with known human immunodeficiency virus (HIV) or hepatitis B or C classes of active viral infection 11. Have a history of neurological or psychiatric disorders, including epilepsy or dementia 12. Subjects for whom ventilator support is required at screening 13. Patients not willing to stay in hospital for 5 days of isolation following diagnosis of Covid-19 14. Subjects not willing to give their informed consent to participate in the clinical trial Subjects having uncontrolled diabetes, uncontrolled hypertension. 16. According to the investigator's judgment, there are concomitant diseases with a serious safety hazard or affect the subject 17. Using other experimental drugs or participating in other clinical trials in the prior one month.