(1)Asymptomatic patients(2)Patients previously diagnosed COVID-19 in the past(3)Known allergy or intolerance to colchicine(4)Patients taking colchicine withing the past 30 days of consent date(5)Patients taking biological drug withing the past 30 days of consent date(6)Patients taking oral or intravenous corticosteroids withing the past 30 days of informed consent date(7)Liver cirrhosis(8)Clinical cholestasis(9)Renal failure (eGFR < 30)(10)Active or previous history of malignant disease(11)Patients taking medicines as listed below:a.Medicines strongly inhibiting CYP3A4Atazanavir, Clarithromycin, Indinavir, Itraconazole, Nelfinavir, Ritonavir, Saquinavir, Darunavir, Telithromycin, Telaprevir, drugs containing kobishistatb.Medicines moderately inhibiting CYP3A4Amprenavir, Aprepitant, Diltiazem, Erythromycin, Fluconazole, Fosamprenavir, Verapamilc.Medicines inhibiting P glycoproteinCyclosporine(12)Patients taking Amiodarone or Quinidine(13)Pregnant or possibly pregnant patients, patients with breastfeeding, patients willing to be pregnant(14)Patients registered in other clinical trials/studies at informed consent date or in the past 30 days of informed consent date(15)Patients being considered as inappropriate by attending physicians

(1)Asymptomatic patients(2)Patients previously diagnosed COVID-19 in the past(3)Known allergy or intolerance to colchicine(4)Patients taking colchicine withing the past 30 days of consent date(5)Patients taking biological drug withing the past 30 days of consent date(6)Patients taking oral or intravenous corticosteroids withing the past 30 days of informed consent date(7)Liver cirrhosis(8)Clinical cholestasis(9)Renal failure (eGFR < 30)(10)Active or previous history of malignant disease(11)Patients taking medicines as listed below:a.Medicines strongly inhibiting CYP3A4Atazanavir, Clarithromycin, Indinavir, Itraconazole, Nelfinavir, Ritonavir, Saquinavir, Darunavir, Telithromycin, Telaprevir, drugs containing kobishistatb.Medicines moderately inhibiting CYP3A4Amprenavir, Aprepitant, Diltiazem, Erythromycin, Fluconazole, Fosamprenavir, Verapamilc.Medicines inhibiting P glycoproteinCyclosporine(12)Patients taking Amiodarone or Quinidine(13)Pregnant or possibly pregnant patients, patients with breastfeeding, patients willing to be pregnant(14)Patients registered in other clinical trials/studies at informed consent date or in the past 30 days of informed consent date(15)Patients being considered as inappropriate by attending physicians