1. patients who have a record of hiv or aids 2. female patients, either who are pregnant within 6 months before the investigation, who breast-fed babies within 3 months before the investigation, or who may get pregnant or breast-feed within 1 month after the investigation is over 3. patients at high risk of death within 3 days of randomized assignment, by the judge of the investigator 4. patients with liver cirrhosis whose child-puch score is b or c 5. patients who have liver disease abnormalities with alt or ast \> 5 times uln 6. patients who can be in danger or who shows clinically-important other conditions which may interfere with the evaluation or completion of the test procedure, as the investigator's opinion 7. patients who are not appropriate for the test, as the investigator's opinion 8. patients who have hypersensitivity to the investigational drug

1. patients who have a record of hiv or aids 2. female patients, either who are pregnant within 6 months before the investigation, who breast-fed babies within 3 months before the investigation, or who may get pregnant or breast-feed within 1 month after the investigation is over 3. patients at high risk of death within 3 days of randomized assignment, by the judge of the investigator 4. patients with liver cirrhosis whose child-puch score is b or c 5. patients who have liver disease abnormalities with alt or ast \> 5 times uln 6. patients who can be in danger or who shows clinically-important other conditions which may interfere with the evaluation or completion of the test procedure, as the investigator's opinion 7. patients who are not appropriate for the test, as the investigator's opinion 8. patients who have hypersensitivity to the investigational drug

patients who have a record of hiv or aids female patients, either who are pregnant within 6 months before the investigation, who breast-fed babies within 3 months before the investigation, or who may get pregnant or breast-feed within 1 month after the investigation is over patients at high risk of death within 3 days of randomized assignment, by the judge of the investigator patients with liver cirrhosis whose child-puch score is b or c patients who have liver disease abnormalities with alt or ast > 5 times uln patients who can be in danger or who shows clinically-important other conditions which may interfere with the evaluation or completion of the test procedure, as the investigator's opinion patients who are not appropriate for the test, as the investigator's opinion patients who have hypersensitivity to the investigational drug

patients who have a record of hiv or aids female patients, either who are pregnant within 6 months before the investigation, who breast-fed babies within 3 months before the investigation, or who may get pregnant or breast-feed within 1 month after the investigation is over patients at high risk of death within 3 days of randomized assignment, by the judge of the investigator patients with liver cirrhosis whose child-puch score is b or c patients who have liver disease abnormalities with alt or ast > 5 times uln patients who can be in danger or who shows clinically-important other conditions which may interfere with the evaluation or completion of the test procedure, as the investigator's opinion patients who are not appropriate for the test, as the investigator's opinion patients who have hypersensitivity to the investigational drug

1. patients who have a record of hiv or aids 2. female patients, either who are pregnant within 6 months before the investigation, who breast-fed babies within 3 months before the investigation, or who may get pregnant or breast-feed within 1 month after the investigation is over 3. patients at high risk of death within 3 days of randomized assignment, by the judge of the investigator 4. patients with liver cirrhosis whose child-puch score is b or c 5. patients who have liver disease abnormalities with alt or ast > 5 times uln 6. patients who can be in danger or who shows clinically-important other conditions which may interfere with the evaluation or completion of the test procedure, as the investigator's opinion 7. patients who are not appropriate for the test, as the investigator's opinion 8. patients who have hypersensitivity to the investigational drug

1. patients who have a record of hiv or aids 2. female patients, either who are pregnant within 6 months before the investigation, who breast-fed babies within 3 months before the investigation, or who may get pregnant or breast-feed within 1 month after the investigation is over 3. patients at high risk of death within 3 days of randomized assignment, by the judge of the investigator 4. patients with liver cirrhosis whose child-puch score is b or c 5. patients who have liver disease abnormalities with alt or ast > 5 times uln 6. patients who can be in danger or who shows clinically-important other conditions which may interfere with the evaluation or completion of the test procedure, as the investigator's opinion 7. patients who are not appropriate for the test, as the investigator's opinion 8. patients who have hypersensitivity to the investigational drug