1. Adult greater than or equal to 18 years, male or non-pregnant female at the time of enrolment. 2. Laboratory confirmed (RT-PCR) COVID-19 infection. 3. Able to give informed consent or by their legal representative for ICU patients who are unable to sign. 4. Must agree to comply with the study procedure. 5. On hospital admission with SPO2 less than or equal to 94% or needs mechanical ventilation or needs supplemental oxygen. 6. Must agree not to join any other clinical trial for COVID-19 throughout this study period [day 1 to day 28]

1. Adult greater than or equal to 18 years, male or non-pregnant female at the time of enrolment. 2. Laboratory confirmed (RT-PCR) COVID-19 infection. 3. Able to give informed consent or by their legal representative for ICU patients who are unable to sign. 4. Must agree to comply with the study procedure. 5. On hospital admission with SPO2 less than or equal to 94% or needs mechanical ventilation or needs supplemental oxygen. 6. Must agree not to join any other clinical trial for COVID-19 throughout this study period [day 1 to day 28]