1. Patients with severely deranged liver function (the hepatic transaminases more than 5x the upper limit of normal). 2. Severely deranged kidney function (with estimated glomerular filtration rate, eGFR less than or equal to 30ml/min/1.73m2 or patients on kidney replacement support). 3. Any plan of discharge in the next 72hours to a hospital that is not one of our study sites. 4. Breast-feeding or pregnant adult female. 5. History of allergy to the study drug. Good to note that women of child-bearing age will be advised and encouraged to adhere to safe and effective contraceptive measures.

1. Patients with severely deranged liver function (the hepatic transaminases more than 5x the upper limit of normal). 2. Severely deranged kidney function (with estimated glomerular filtration rate, eGFR less than or equal to 30ml/min/1.73m2 or patients on kidney replacement support). 3. Any plan of discharge in the next 72hours to a hospital that is not one of our study sites. 4. Breast-feeding or pregnant adult female. 5. History of allergy to the study drug. Good to note that women of child-bearing age will be advised and encouraged to adhere to safe and effective contraceptive measures.