1. Aged 18 years and above, 2. Able to understand the content of informed consent and willing to sign the informed consent, 3. Able and willing to complete all the secluded study process during the whole study follow-up period (about 6 months), 4. Axillary temperature <=37.0 degree C, 5. General good health as established by medical history and physical examination.

1. Aged 18 years and above, 2. Able to understand the content of informed consent and willing to sign the informed consent, 3. Able and willing to complete all the secluded study process during the whole study follow-up period (about 6 months), 4. Axillary temperature <=37.0 degree C, 5. General good health as established by medical history and physical examination.