Man or woman, aged 60 years or over, with laboratory confirmation of the infection (COVID-19) by polymerase chain reaction with reverse transcription (RT-PCR), presence of at least one risk factor (co-morbidity) beyond age, adequate and healthy hematological values, hemoglobin 100 g / L, neutrophils 1.0 x 10 (9) / L, platelets 150 x 10 (9) / L, adequate livre function, ALT and AST 2.5 x ULN, bilirubin 1.5 x ULN,Adequate renal function, calculated creatinine clearance 50 mL / min, written informed consent signed by the candidate.

Man or woman, aged 60 years or over, with laboratory confirmation of the infection (COVID-19) by polymerase chain reaction with reverse transcription (RT-PCR), presence of at least one risk factor (co-morbidity) beyond age, adequate and healthy hematological values, hemoglobin 100 g / L, neutrophils 1.0 x 10 (9) / L, platelets 150 x 10 (9) / L, adequate livre function, ALT and AST 2.5 x ULN, bilirubin 1.5 x ULN,Adequate renal function, calculated creatinine clearance 50 mL / min, written informed consent signed by the candidate.