inclusion criteria: * phase ia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃. * phase iia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃.

inclusion criteria: * phase ia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃. * phase iia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃.

inclusion criteria: phase ia: healthy adults aged 18 to 59 years (including boundary values), both men and women. proven legal identity. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. axillary temperature ≤37.0 ℃. phase iia: healthy adults aged 18 to 59 years (including boundary values), both men and women. proven legal identity. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. axillary temperature ≤37.0 ℃.

inclusion criteria: phase ia: healthy adults aged 18 to 59 years (including boundary values), both men and women. proven legal identity. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. axillary temperature ≤37.0 ℃. phase iia: healthy adults aged 18 to 59 years (including boundary values), both men and women. proven legal identity. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. axillary temperature ≤37.0 ℃.

inclusion criteria: - phase ia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃. - phase iia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃.

inclusion criteria: - phase ia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃. - phase iia: 1. healthy adults aged 18 to 59 years (including boundary values), both men and women. 2. proven legal identity. 3. participants should understand the contents of the informed consent form, the vaccine in this trial, voluntarily sign the informed consent form, and be capable of using thermometers, scales, and filling in diary cards and contact cards as required. 4. participants should be able to communicate well with investigators, understand and comply with the requirements of this trial. 5. axillary temperature ≤37.0 ℃.