1.Severe infection News-3-4 requiring admission to ICU. <br/ >2.Unable to take oral medication, <br/ >3.Immunocompromised, <br/ >4.Creatinine clearance (CCL) < 30 ml/min, <br/ >5.Aspartate transaminase (AST) or alanine transaminase (ALT) > 5 times Upper limit of normal (ULN), <br/ >6.d-dimer > 2microgram per liter, or <br/ >7.Uncontrolled diabetes, Hypertension, Existing Heart disease and heart failure, any cancer, autoimmune disease, stroke, neurodegenerative diseases etc.. <br/ >8.Clinical condition that reduces survival to less than six months. <br/ >9.Pregnancy and lactating mothers <br/ >10.Clinical signs suggestive of septicemia and multi organ dysfunction. <br/ >11. Score of less than 24 points on the Folstein Mini-Mental State Examination(43). <br/ >12.Score of more than 14 points on the 9-item Patient Health Questionnaire (PHQ-9) depression screen (44). <br/ >13.BMI less than 18 <br/ >

1.Severe infection News-3-4 requiring admission to ICU. <br/ >2.Unable to take oral medication, <br/ >3.Immunocompromised, <br/ >4.Creatinine clearance (CCL) < 30 ml/min, <br/ >5.Aspartate transaminase (AST) or alanine transaminase (ALT) > 5 times Upper limit of normal (ULN), <br/ >6.d-dimer > 2microgram per liter, or <br/ >7.Uncontrolled diabetes, Hypertension, Existing Heart disease and heart failure, any cancer, autoimmune disease, stroke, neurodegenerative diseases etc.. <br/ >8.Clinical condition that reduces survival to less than six months. <br/ >9.Pregnancy and lactating mothers <br/ >10.Clinical signs suggestive of septicemia and multi organ dysfunction. <br/ >11. Score of less than 24 points on the Folstein Mini-Mental State Examination(43). <br/ >12.Score of more than 14 points on the 9-item Patient Health Questionnaire (PHQ-9) depression screen (44). <br/ >13.BMI less than 18 <br/ >

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1.Severe infection News-3-4 requiring admission to ICU. <br/ >2.Unable to take oral medication, <br/ >3.Immunocompromised, <br/ >4.Creatinine clearance (CCL) < 30 ml/min, <br/ >5.Aspartate transaminase (AST) or alanine transaminase (ALT) > 5 times Upper limit of normal (ULN), <br/ >6.d-dimer > 2microgram per liter, or <br/ >7.Uncontrolled diabetes, Hypertension, Existing Heart disease and heart failure, any cancer, autoimmune disease, stroke, neurodegenerative diseases etc.. <br/ >8.Clinical condition that reduces survival to less than six months. <br/ >9.Pregnancy and lactating mothers <br/ >10.Clinical signs suggestive of septicemia and multi organ dysfunction. <br/ >11. Score of less than 24 points on the Folstein Mini-Mental State Examination(43). <br/ >12.Score of more than 14 points on the 9-item Patient Health Questionnaire (PHQ-9) depression screen (44). <br/ >13.BMI less than 18 <br/ >

1.Severe infection News-3-4 requiring admission to ICU. <br/ >2.Unable to take oral medication, <br/ >3.Immunocompromised, <br/ >4.Creatinine clearance (CCL) < 30 ml/min, <br/ >5.Aspartate transaminase (AST) or alanine transaminase (ALT) > 5 times Upper limit of normal (ULN), <br/ >6.d-dimer > 2microgram per liter, or <br/ >7.Uncontrolled diabetes, Hypertension, Existing Heart disease and heart failure, any cancer, autoimmune disease, stroke, neurodegenerative diseases etc.. <br/ >8.Clinical condition that reduces survival to less than six months. <br/ >9.Pregnancy and lactating mothers <br/ >10.Clinical signs suggestive of septicemia and multi organ dysfunction. <br/ >11. Score of less than 24 points on the Folstein Mini-Mental State Examination(43). <br/ >12.Score of more than 14 points on the 9-item Patient Health Questionnaire (PHQ-9) depression screen (44). <br/ >13.BMI less than 18 <br/ >