* known hypersensitivity to hcq or other 4-aminoquinoline compounds * history of retinopathy of any aetiology * concomitant use of digoxin, cyclosporine, cimetidine * known liver disease * clinical history of cardiac pathology including known long qt syndrome * unable to cooperate with the requirements of the study * participating in other intervention studies * delivery onset (characterized by painful uterine contractions and variable changes of the cervix, including some degree of effacement and slower progression of dilatation up to 5 cm for first and subsequent labours)

* known hypersensitivity to hcq or other 4-aminoquinoline compounds * history of retinopathy of any aetiology * concomitant use of digoxin, cyclosporine, cimetidine * known liver disease * clinical history of cardiac pathology including known long qt syndrome * unable to cooperate with the requirements of the study * participating in other intervention studies * delivery onset (characterized by painful uterine contractions and variable changes of the cervix, including some degree of effacement and slower progression of dilatation up to 5 cm for first and subsequent labours)

- known hypersensitivity to hcq or other 4-aminoquinoline compounds - history of retinopathy of any aetiology - concomitant use of digoxin, cyclosporine, cimetidine - known liver disease - clinical history of cardiac pathology including known long qt syndrome - unable to cooperate with the requirements of the study - participating in other intervention studies - delivery onset (characterized by painful uterine contractions and variable changes of the cervix, including some degree of effacement and slower progression of dilatation up to 5 cm for first and subsequent labours)

- known hypersensitivity to hcq or other 4-aminoquinoline compounds - history of retinopathy of any aetiology - concomitant use of digoxin, cyclosporine, cimetidine - known liver disease - clinical history of cardiac pathology including known long qt syndrome - unable to cooperate with the requirements of the study - participating in other intervention studies - delivery onset (characterized by painful uterine contractions and variable changes of the cervix, including some degree of effacement and slower progression of dilatation up to 5 cm for first and subsequent labours)