1. Subjects over 18 years old at the time of enrollment, 2. The subjects who can comply with the requirements of the clinical study protocol, complete all the trial procedures, and sign the informed consent form, 3. Since December 2019, the subjects who have not been to the epidemic area, have not contacted the new coronal infection or suspected cases, and are in the non isolation period, and there are no new coronal infection or suspected cases in the same village / community, 4. New Coronavirus total antibody test (colloidal gold method) negative subjects, 5. For female subjects, they should have no pregnancy plan within 12 months after the first dose of vaccine and agree to use effective contraceptive measures.

1. Subjects over 18 years old at the time of enrollment, 2. The subjects who can comply with the requirements of the clinical study protocol, complete all the trial procedures, and sign the informed consent form, 3. Since December 2019, the subjects who have not been to the epidemic area, have not contacted the new coronal infection or suspected cases, and are in the non isolation period, and there are no new coronal infection or suspected cases in the same village / community, 4. New Coronavirus total antibody test (colloidal gold method) negative subjects, 5. For female subjects, they should have no pregnancy plan within 12 months after the first dose of vaccine and agree to use effective contraceptive measures.

1. Be at least 18 years old at the time of enrollment, 2. Be able to comply with the requirements of clinical research protocol, complete all trial procedures, and sign the informed consent form, 3. Since December 2019, those who have not been to an area where an epidemic has occurred, have not been in contact with a person with a SARS-CoV-2 infection or a suspected case, a person in a non-quarantine period, and there has been no SARS-CoV-2 infected person or a suspected case in the same village/community, 4. SARS-CoV-2 total antibody test (colloidal gold method) is negative, 5. For female subjects, they must have no pregnancy plan within 12 months after the first dose of vaccination and agree to use effective contraceptive measures.

1. Be at least 18 years old at the time of enrollment, 2. Be able to comply with the requirements of clinical research protocol, complete all trial procedures, and sign the informed consent form, 3. Since December 2019, those who have not been to an area where an epidemic has occurred, have not been in contact with a person with a SARS-CoV-2 infection or a suspected case, a person in a non-quarantine period, and there has been no SARS-CoV-2 infected person or a suspected case in the same village/community, 4. SARS-CoV-2 total antibody test (colloidal gold method) is negative, 5. For female subjects, they must have no pregnancy plan within 12 months after the first dose of vaccination and agree to use effective contraceptive measures.