1. Subjects who give their informed consent to participate in the study by writing. 2. Subjects aged between 19 and 59 years. 3. Body mass index between 18.5 and 29.9 kg / m2. 4. Women of childbearing potential use safe contraceptive methods during the study. 5. General, regional and apparatus physical examination: normal or without clinically significant alterations. 6. Laboratory results within or outside the range of reference values ??but not clinically significant

1. Subjects who give their informed consent to participate in the study by writing. 2. Subjects aged between 19 and 59 years. 3. Body mass index between 18.5 and 29.9 kg / m2. 4. Women of childbearing potential use safe contraceptive methods during the study. 5. General, regional and apparatus physical examination: normal or without clinically significant alterations. 6. Laboratory results within or outside the range of reference values ??but not clinically significant