1. Patients on ventilators (invasive/non-invasive) <br/ >2. Prior lobectomy or pneumonectomy <br/ >3. Prior thoracic radiotherapy resulting in a maximum lung dose of 100 cGy or higher within 14 days of enrollment <br/ >4. Prior chemotherapy or other systemic therapy with potential for pulmonary toxicity or radio sensitization within 14 days or 5 half-lives, whichever is greater, of enrollment, e.g., bleomycin, gemcitabine <br/ >5. Prior cancer immunotherapy with an immune checkpoint inhibitor within 60 days of enrollment <br/ >6. Severe pre-existing heart disease, e.g., New York Heart Association (NYHA) functional class 3 (or higher) congestive heart failure <br/ >7. History of bone marrow or solid organ transplantation <br/ >8. Known history of autoimmune collagen vascular disease, e.g., scleroderma <br/ >9. Known hereditary syndrome with increased sensitivity to ionizing radiation, e.g., ataxia-telangiectasia or Fanconi anemia <br/ >10. Pregnancy <br/ >11. Inability to be positioned supine and flat for radiation planning and delivery <br/ >12. Inability to provide informed consent or lack of an authorized representative who can provide informed consent

1. Patients on ventilators (invasive/non-invasive) <br/ >2. Prior lobectomy or pneumonectomy <br/ >3. Prior thoracic radiotherapy resulting in a maximum lung dose of 100 cGy or higher within 14 days of enrollment <br/ >4. Prior chemotherapy or other systemic therapy with potential for pulmonary toxicity or radio sensitization within 14 days or 5 half-lives, whichever is greater, of enrollment, e.g., bleomycin, gemcitabine <br/ >5. Prior cancer immunotherapy with an immune checkpoint inhibitor within 60 days of enrollment <br/ >6. Severe pre-existing heart disease, e.g., New York Heart Association (NYHA) functional class 3 (or higher) congestive heart failure <br/ >7. History of bone marrow or solid organ transplantation <br/ >8. Known history of autoimmune collagen vascular disease, e.g., scleroderma <br/ >9. Known hereditary syndrome with increased sensitivity to ionizing radiation, e.g., ataxia-telangiectasia or Fanconi anemia <br/ >10. Pregnancy <br/ >11. Inability to be positioned supine and flat for radiation planning and delivery <br/ >12. Inability to provide informed consent or lack of an authorized representative who can provide informed consent

N/A

N/A

1. Patients on ventilators (invasive/non-invasive) <br/ >2. Prior lobectomy or pneumonectomy <br/ >3. Prior thoracic radiotherapy resulting in a maximum lung dose of 100 cGy or higher within 14 days of enrollment <br/ >4. Prior chemotherapy or other systemic therapy with potential for pulmonary toxicity or radio sensitization within 14 days or 5 half-lives, whichever is greater, of enrollment, e.g., bleomycin, gemcitabine <br/ >5. Prior cancer immunotherapy with an immune checkpoint inhibitor within 60 days of enrollment <br/ >6. Severe pre-existing heart disease, e.g., New York Heart Association (NYHA) functional class 3 (or higher) congestive heart failure <br/ >7. History of bone marrow or solid organ transplantation <br/ >8. Known history of autoimmune collagen vascular disease, e.g., scleroderma <br/ >9. Known hereditary syndrome with increased sensitivity to ionizing radiation, e.g., ataxia-telangiectasia or Fanconi anemia <br/ >10. Pregnancy <br/ >11. Inability to be positioned supine and flat for radiation planning and delivery <br/ >12. Inability to provide informed consent or lack of an authorized representative who can provide informed consent

1. Patients on ventilators (invasive/non-invasive) <br/ >2. Prior lobectomy or pneumonectomy <br/ >3. Prior thoracic radiotherapy resulting in a maximum lung dose of 100 cGy or higher within 14 days of enrollment <br/ >4. Prior chemotherapy or other systemic therapy with potential for pulmonary toxicity or radio sensitization within 14 days or 5 half-lives, whichever is greater, of enrollment, e.g., bleomycin, gemcitabine <br/ >5. Prior cancer immunotherapy with an immune checkpoint inhibitor within 60 days of enrollment <br/ >6. Severe pre-existing heart disease, e.g., New York Heart Association (NYHA) functional class 3 (or higher) congestive heart failure <br/ >7. History of bone marrow or solid organ transplantation <br/ >8. Known history of autoimmune collagen vascular disease, e.g., scleroderma <br/ >9. Known hereditary syndrome with increased sensitivity to ionizing radiation, e.g., ataxia-telangiectasia or Fanconi anemia <br/ >10. Pregnancy <br/ >11. Inability to be positioned supine and flat for radiation planning and delivery <br/ >12. Inability to provide informed consent or lack of an authorized representative who can provide informed consent