Created at Source Raw Value Validated value
Nov. 26, 2021, 10:30 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Low Dose Radiation therapy in addition to standard pharmacological therapy: Low dose radiotherapy using a Linear accelerator to bilateral whole lungs as a single fraction treatment with a dose of 0.5 Gy in addition to pharmacological therapy based on guidelines devised by Ministry of Health and Family welfare; IndiaDexamethasone 6mg IV Once daily for 10 days; (Alternative: Methylprednisolone 80mg IV BD for 10 days)Enoxiparin 60mg s/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response; Convalescent plasma One or two units (approximately 200-250ml per unit); Tocilizumab 400mg IV as a single dose (repeat dose in 12 to 24 hours if patient\u00e2??s condition has notimproved); Vitamin D 60;000U /week; Vitamin C 1500 mg/day;Zinc;Paracetamol; Anti-tussives; Antibiotics;Oxygen supplementation. Adjunctive therapies : IV thiamine;IV vitamin C; N acetyl cysteine; Ulinastatin; Sepsivac (mycobacterium w); high dose statins. Salvage therapies : Pulse therapy of steroids; Cytosorb-hemoperfusion; Pirfenidone;Alteplase.The pharmacologic therapy is individualized on a case by case basis.Control Intervention1: Standard Pharmacological Therapy only: Pharmacological therapy based on guidelines devised by Ministry of Health and Family welfare; India.Dexamethasone 6mg IV Once daily for 10 days (Alternative: Methylprednisolone 80mg IV BD for 10 days); Enoxiparin 60mg s/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response; Convalescent plasma One or two units (approximately 200-", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 746, "treatment_name": "Low dose radiation therapy", "treatment_type": "Radiation therapy", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]

Nov. 13, 2021, 5:33 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "N/A", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

Nov. 6, 2020, 11:45 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Low Dose Radiation therapy in addition to standard pharmacological therapy: Low dose radiotherapy using a Linear accelerator to bilateral whole lungs as a single fraction treatment with a dose of 0.5 Gy in addition to pharmacological therapy based on guidelines devised by Ministry of Health and Family welfare; IndiaDexamethasone 6mg IV Once daily for 10 days; (Alternative: Methylprednisolone 80mg IV BD for 10 days)Enoxiparin 60mg s/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response; Convalescent plasma One or two units (approximately 200-250ml per unit); Tocilizumab 400mg IV as a single dose (repeat dose in 12 to 24 hours if patient\u00e2??s condition has notimproved); Vitamin D 60;000U /week; Vitamin C 1500 mg/day;Zinc;Paracetamol; Anti-tussives; Antibiotics;Oxygen supplementation. Adjunctive therapies : IV thiamine;IV vitamin C; N acetyl cysteine; Ulinastatin; Sepsivac (mycobacterium w); high dose statins. Salvage therapies : Pulse therapy of steroids; Cytosorb-hemoperfusion; Pirfenidone;Alteplase.The pharmacologic therapy is individualized on a case by case basis.Control Intervention1: Standard Pharmacological Therapy only: Pharmacological therapy based on guidelines devised by Ministry of Health and Family welfare; India.Dexamethasone 6mg IV Once daily for 10 days (Alternative: Methylprednisolone 80mg IV BD for 10 days); Enoxiparin 60mg s/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response; Convalescent plasma One or two units (approximately 200-", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]