1. Known case of severe allergic reactions to <br/ > monoclonal antibodies <br/ >2. Active tuberculosis (TB) infection <br/ >3. History of inadequately treated tuberculosis <br/ > or latent tuberculosis <br/ >4. Have received oral anti-rejection or immune- <br/ > suppressive drugs within the past 6 months <br/ >5. Pregnant or breastfeeding, or positive <br/ > pregnancy test in a pre-dose examination <br/ >6. Patients with known history of Hepatitis <br/ > B, Hepatitis C or HIV <br/ >7. Absolute Neutrophils count (ANC) <1000 / mm3 <br/ >8. Platelets <50,000 / mm3 <br/ >9. Absolute Lymphocyte count (ALC): <500/mm3 <br/ >10. Very severe ARDS Pao2/Fio2â?¤100 with PEEPâ?¥5 <br/ >11. ARDS due to others secondary infection/ <br/ > bacterial sepsis (High procalcitonin value) <br/ >12. Those patient who will be recruited for <br/ > another study <br/ >

1. Known case of severe allergic reactions to <br/ > monoclonal antibodies <br/ >2. Active tuberculosis (TB) infection <br/ >3. History of inadequately treated tuberculosis <br/ > or latent tuberculosis <br/ >4. Have received oral anti-rejection or immune- <br/ > suppressive drugs within the past 6 months <br/ >5. Pregnant or breastfeeding, or positive <br/ > pregnancy test in a pre-dose examination <br/ >6. Patients with known history of Hepatitis <br/ > B, Hepatitis C or HIV <br/ >7. Absolute Neutrophils count (ANC) <1000 / mm3 <br/ >8. Platelets <50,000 / mm3 <br/ >9. Absolute Lymphocyte count (ALC): <500/mm3 <br/ >10. Very severe ARDS Pao2/Fio2â?¤100 with PEEPâ?¥5 <br/ >11. ARDS due to others secondary infection/ <br/ > bacterial sepsis (High procalcitonin value) <br/ >12. Those patient who will be recruited for <br/ > another study <br/ >

N/A

N/A

1. Known case of severe allergic reactions to <br/ > monoclonal antibodies <br/ >2. Active tuberculosis (TB) infection <br/ >3. History of inadequately treated tuberculosis <br/ > or latent tuberculosis <br/ >4. Have received oral anti-rejection or immune- <br/ > suppressive drugs within the past 6 months <br/ >5. Pregnant or breastfeeding, or positive <br/ > pregnancy test in a pre-dose examination <br/ >6. Patients with known history of Hepatitis <br/ > B, Hepatitis C or HIV <br/ >7. Absolute Neutrophils count (ANC) <1000 / mm3 <br/ >8. Platelets <50,000 / mm3 <br/ >9. Absolute Lymphocyte count (ALC): <500/mm3 <br/ >10. Very severe ARDS Pao2/Fio2â?¤100 with PEEPâ?¥5 <br/ >11. ARDS due to others secondary infection/ <br/ > bacterial sepsis (High procalcitonin value) <br/ >12. Those patient who will be recruited for <br/ > another study <br/ >

1. Known case of severe allergic reactions to <br/ > monoclonal antibodies <br/ >2. Active tuberculosis (TB) infection <br/ >3. History of inadequately treated tuberculosis <br/ > or latent tuberculosis <br/ >4. Have received oral anti-rejection or immune- <br/ > suppressive drugs within the past 6 months <br/ >5. Pregnant or breastfeeding, or positive <br/ > pregnancy test in a pre-dose examination <br/ >6. Patients with known history of Hepatitis <br/ > B, Hepatitis C or HIV <br/ >7. Absolute Neutrophils count (ANC) <1000 / mm3 <br/ >8. Platelets <50,000 / mm3 <br/ >9. Absolute Lymphocyte count (ALC): <500/mm3 <br/ >10. Very severe ARDS Pao2/Fio2â?¤100 with PEEPâ?¥5 <br/ >11. ARDS due to others secondary infection/ <br/ > bacterial sepsis (High procalcitonin value) <br/ >12. Those patient who will be recruited for <br/ > another study <br/ >