Created at Source Raw Value Validated value
May 27, 2021, 12:45 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Patients treated at home: Group I (experimental 1): Nebulization with Homeostec (5 ml) + Paracetamol (500 mg). The patient will receive a bottle with 5 ml of Homeostec (electrolysed solution with neutral pH); which will be placed in the nebulizer container. The patient will receive sprays for 15 min; four times a day for 7 days. In addition; you can take Paracetamol 500 mg (orally) every 6 hours. Other medications may be added at the discretion of the treating physician as deemed necessary for the patient. Group II (experimental 2): Nebulization with Homeostec (5 ml) + Paracetamol (500 mg) + Homeostec intravenously (15 ml; with dose escalation). The patient will receive a bottle with 5 ml of Homeostec (neutral pH electrolyzed solution); which will be placed in the nebulizer container. The patient will receive sprays for 15 min; four times a day for 7 days. Additionally; 15 ml of Homeostec will be administered intravenously loaded in a 20 ml syringe. The solution will be applied to an arm vein using a butterfly-type IV application catheter connected to the syringe; in a period of 1 to 2 min; once every 24 hours for 7 days; by research personnel who will visit the patient in his home. The initial intravenous dose of 15ml per day will have successive increments; before reaching dose-limiting toxicity; or until a dose was found that prevented disease progression. In addition; you can take Paracetamol 500 mg (orally) every 6 hours. Other medications may be added at the discretion of the treating physician as deemed necessary for the patient. Group III (control 1; usual medical care): Paracetamol (500 mg). The patient will receive Paracetamol 500 mg (orally) every 6 hours. Other medications may be added at the discretion of the treating physician as deemed necessa;Saline Solution;Acetaminophen;Tablets;Administration; Intravenous;Administration; Oral;Administration; Inhalation;Homeostec; Paracetamol", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "nubilization", "treatment_id": 586, "treatment_name": "Homeostec", "treatment_type": "Others pharmacological treatment", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "nebulization+IV", "treatment_id": 586, "treatment_name": "Homeostec", "treatment_type": "Others pharmacological treatment", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "IV", "treatment_id": 586, "treatment_name": "Homeostec", "treatment_type": "Others pharmacological treatment", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]

Oct. 26, 2020, 8:29 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Patients treated at home: Group I (experimental 1): Nebulization with Homeostec (5 ml) + Paracetamol (500 mg). The patient will receive a bottle with 5 ml of Homeostec (electrolysed solution with neutral pH); which will be placed in the nebulizer container. The patient will receive sprays for 15 min; four times a day for 7 days. In addition; you can take Paracetamol 500 mg (orally) every 6 hours.Other medications may be added at the discretion of the treating physician as deemed necessary for the patient. Group II (experimental 2): Nebulization with Homeostec (5 ml) + Paracetamol (500 mg) + Homeostec intravenously (15 ml; with dose escalation). The patient will receive a bottle with 5 ml of Homeostec (neutral pH electrolyzed solution); which will be placed in the nebulizer container. The patient will receive sprays for 15 min; four times a day for 7 days. Additionally; 15 ml of Homeostec will be administered intravenously loaded in a 20 ml syringe. The solution will be applied to an arm vein using a butterfly-type IV application catheter connected to the syringe; in a period of 1 to 2 min; once every 24 hours for 7 days; by research personnel who will visit the patient in his home. The initial intravenous dose of 15ml per day will have successive increments; before reaching dose-limiting toxicity; or until a dose was found that prevented disease progression. In addition; you can take Paracetamol 500 mg (orally) every 6 hours. Other medications may be added at the discretion of the treating physician as deemed necessary for the patient. Group III (control 1; usual medical care): Paracetamol (500 mg). The patient will receive Paracetamol 500 mg (orally) every 6 hours. Other medications may be added at the discretion of the treating physician as deemed necessary for the p;Saline Solution;Homeostec; Paracetamol", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]