Activation of markers of the innate immune system (in oropharyngeal scraping: relative concentration of dendritic cells; phenotypic analysis of leukocyte cells; transcriptional analysis of elements of molecules related to the immune response with expression at the level of epithelium and infiltrating leukocytes; quantification by ELISA of cytokines related to systemic inflammation such as IL-6; TNF alpha; IFN alpha and gamma; among other mediators of systemic inflammation; etc.). Measurement time: at baseline and; on days 4 and 8 post-treatment.

Activation of markers of the innate immune system (in oropharyngeal scraping: relative concentration of dendritic cells; phenotypic analysis of leukocyte cells; transcriptional analysis of elements of molecules related to the immune response with expression at the level of epithelium and infiltrating leukocytes; quantification by ELISA of cytokines related to systemic inflammation such as IL-6; TNF alpha; IFN alpha and gamma; among other mediators of systemic inflammation; etc.). Measurement time: at baseline and; on days 4 and 8 post-treatment.