Individuals who meet at least one of the following criteria will be excluded from the study: negative result of RT-PCR for SARS-COV2 collected on admission, impossibility to use oral medications, history of severe liver disease (Child Pugh C class), previous renal failure: patients undergoing dialysis, severe heart failure (NYHA 3 or 4), COPD (GOLD 3 and 4), neoplasia in the last 5 years, known autoimmune disease, individuals with known hypersensitivity to study drugs, previous treatment with the study medication during the last 30 days, clinical suspicion of tuberculosis and bacterial pneumonia.

Individuals who meet at least one of the following criteria will be excluded from the study: negative result of RT-PCR for SARS-COV2 collected on admission, impossibility to use oral medications, history of severe liver disease (Child Pugh C class), previous renal failure: patients undergoing dialysis, severe heart failure (NYHA 3 or 4), COPD (GOLD 3 and 4), neoplasia in the last 5 years, known autoimmune disease, individuals with known hypersensitivity to study drugs, previous treatment with the study medication during the last 30 days, clinical suspicion of tuberculosis and bacterial pneumonia.