Created at Source Raw Value Validated value
Dec. 15, 2020, 2:47 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention group - a total of 20 participants will be allocated to the intervention group. Hyperbaric oxygen therapy sessions will be held daily and for five consecutive days. A pressure of 2.0 ATA (202.65 kPa) will be used with the patient breathing 100% oxygen in a hyperbaric chamber; from a manufacturer approved by ANVISA; for sixty minutes; without breaking the air and with continuous ventilation. To mitigate the risks of collective and cross-contamination; each chamber will respect a strict hygiene process; described in the appropriate section; and will be dedicated to the exclusive treatment of patients with COVID-19 or suspected COVID-19. The team responsible for the hyperbaric treatment will use personal protective equipment (PPE) and will follow the safety procedures for the administration of hyperbaric oxygen in order to mitigate the possibilities of cross-infection and spread of the coronavirus.Control group - a total of 20 participants will be allocated to the control group.The control group sessions will take place in a hyperbaric chamber; where the patient will be submitted to a sham program with daily sessions for 5 consecutive days with a pressure of 1.2 ATA (absolute pressure atmospheres) which is not considered to be an effective treatment as it will not reach minimal levels capable of producing a therapeutic effect systemically.Co-intervention for both groups (intervention and control groups): Patients will receive standard treatment for COVID-19; inlcuding volume replacement; oral or enteral nutritional therapy; respiratory and motor physical therapy; oxygen and standard antibiotic therapy and medications prescribed by the treating physicians. Standardized routine tests prescribed by each treatment unit ara also allowed (complete bl;Other;E02.880.690.490", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 608, "treatment_name": "Hyperbaric oxygen", "treatment_type": "Gas inhalation", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]

Oct. 26, 2020, 8:29 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention group - a total of 20 participants will be allocated to the intervention group. Hyperbaric oxygen therapy sessions will be held daily and for five consecutive days. A pressure of 2.0 ATA (202.65 kPa) will be used with the patient breathing 100% oxygen in a hyperbaric chamber; from a manufacturer approved by ANVISA; for sixty minutes; without breaking the air and with continuous ventilation. To mitigate the risks of collective and cross-contamination; each chamber will respect a strict hygiene process; described in the appropriate section; and will be dedicated to the exclusive treatment of patients with COVID-19 or suspected COVID-19. The team responsible for the hyperbaric treatment will use personal protective equipment (PPE) and will follow the safety procedures for the administration of hyperbaric oxygen in order to mitigate the possibilities of cross-infection and spread of the coronavirus.Control group - a total of 20 participants will be allocated to the control group.The control group sessions will take place in a hyperbaric chamber; where the patient will be submitted to a sham program with daily sessions for 5 consecutive days with a pressure of 1.2 ATA (absolute pressure atmospheres) which is not considered to be an effective treatment as it will not reach minimal levels capable of producing a therapeutic effect systemically.Co-intervention for both groups (intervention and control groups): Patients will receive standard treatment for COVID-19; inlcuding volume replacement; oral or enteral nutritional therapy; respiratory and motor physical therapy; oxygen and standard antibiotic therapy and medications prescribed by the treating physicians. Standardized routine tests prescribed by each treatment unit ara also allowed (complete bl;Other;Hyperbaric Oxygenation", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]