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Oct. 26, 2020, 8:29 a.m. oms

Participants are excluded from the study if any of the following criteria apply: 1. Known hypersensitivity to any of the study drugs 2. Currently hospitalized 3. Signs of respiratory distress prior to randomization, including respiratory rate >24 per minute and/or SpO2 < 93% 4. Chronic kidney disease (Stage IV or receiving dialysis) 5. Known liver disease or cirrhosis 6. Known personal or family history of long QT syndrome 7. Taking chronic medications associated with prolonged QT and may induce Torsades de Pointes as per CredibleMeds.org, including certain antipsychotic medications or antidepressants (e.g., citalopram, venlafaxine, and bupropion) and unable to stop during the trial 8. Baseline QTc interval of > 470 ms in males, and > 480 ms in females if indicated by the safety profile of the investigational product 9. Potentially clinically significant pharmacokinetic and pharmacodynamic drug interactions as determined by the study clinical pharmacologist* 10. Currently participating in a clinical trial currently or within 30 days of randomization.

Participants are excluded from the study if any of the following criteria apply: 1. Known hypersensitivity to any of the study drugs 2. Currently hospitalized 3. Signs of respiratory distress prior to randomization, including respiratory rate >24 per minute and/or SpO2 < 93% 4. Chronic kidney disease (Stage IV or receiving dialysis) 5. Known liver disease or cirrhosis 6. Known personal or family history of long QT syndrome 7. Taking chronic medications associated with prolonged QT and may induce Torsades de Pointes as per CredibleMeds.org, including certain antipsychotic medications or antidepressants (e.g., citalopram, venlafaxine, and bupropion) and unable to stop during the trial 8. Baseline QTc interval of > 470 ms in males, and > 480 ms in females if indicated by the safety profile of the investigational product 9. Potentially clinically significant pharmacokinetic and pharmacodynamic drug interactions as determined by the study clinical pharmacologist* 10. Currently participating in a clinical trial currently or within 30 days of randomization.