The overall objective of the study is to evaluate the clinical efficacy of different investigational therapeutics relative to the control arm in adults hospitalized with COVID-19.-The primary objective will be determined by a pilot study of the first 100 subjects.-Subject clinical status (8-point ordinal scale) at Day 15 is the default primary endpoint.

The overall objective of the study is to evaluate the clinical efficacy of different investigational therapeutics relative to the control arm in adults hospitalized with COVID-19.-The primary objective will be determined by a pilot study of the first 100 subjects.-Subject clinical status (8-point ordinal scale) at Day 15 is the default primary endpoint.