1.ALT/AST > 5 times the upper limit of normal.2.Estimated glomerular filtration rate (eGFR) < 50 or requiring dialysis.3.Pregnancy or breast feeding.4.Anticipated transfer to another hospital which is not a study site within 72 hours.5.Allergy to any study medication.

1.ALT/AST > 5 times the upper limit of normal.2.Estimated glomerular filtration rate (eGFR) < 50 or requiring dialysis.3.Pregnancy or breast feeding.4.Anticipated transfer to another hospital which is not a study site within 72 hours.5.Allergy to any study medication.