1. Age 18 year or older 2. Admission to a hospital with confirmed or strongly suspected COVID-19 infection 3. Hypoxic respiratory failure defined as a PaO2/FiO2 ratio = 20 kPa (150 mmHg) and/or a FiO2 of = 0.5 to reach a SpO2 of 94% for more than 1 hour 4. Oxygen supplementation (ongoing or planned) with high flow nasal cannuale or noninvasive ventilating support

1. Age 18 year or older 2. Admission to a hospital with confirmed or strongly suspected COVID-19 infection 3. Hypoxic respiratory failure defined as a PaO2/FiO2 ratio = 20 kPa (150 mmHg) and/or a FiO2 of = 0.5 to reach a SpO2 of 94% for more than 1 hour 4. Oxygen supplementation (ongoing or planned) with high flow nasal cannuale or noninvasive ventilating support