Created at Source Raw Value Validated value
Oct. 26, 2020, 8:29 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "This will be a randomized parallel-group study of three groups of COVID-positive Nigerian patients with 10 - 15 post-exposure COVID-positive subjects in each treatment arm. There shall be three treatment groups allotted by randomization. A. 10 - 15 patients receive ivermectin 6 mg twice a week for 2 consecutive weeks (hour 0 and hour 84 or 3.5 days) B. 10 - 15 patients receive Ivermectin 12 mg twice a week for 2 consecutive weeks (hour 0 and hour 84 or 3.5 days) C. 10 - 15 patients receive a matching inactive placebo from a pharmacist who will not be part of the treatment team Randomization: The researchers hope to employ a standard clinical pharmacological randomization tool. Sequential patients will be assigned by chance to one of three treatments; A; B; or C (ratio 1:1:1); by random numbers or asking the patient to select from A B or C labelled papers or balls. This sequence shall be followed until the convenient sample of 10 - 15 is attained in each of the three groups. The total duration of follow up will be about 4 weeks after dosing in the first instance but long-term follow-up will continue as the clinical situation dictates.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "A. 10 - 15 patients receive ivermectin 6 mg twice a week for 2 consecutive weeks (hour 0 and hour 84 or 3.5 days)", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "B. 10 - 15 patients receive Ivermectin 12 mg twice a week for 2 consecutive weeks (hour 0 and hour 84 or 3.5 days)", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "C. 10 - 15 patients receive a matching inactive placebo from a pharmacist who will not be part of the treatment team", "treatment_type": "Placebo", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 693, "treatment_name": "Ivermectin", "treatment_type": "Antiparasitics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 693, "treatment_name": "Ivermectin", "treatment_type": "Antiparasitics", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]