inclusion criteria: 1. respiratory rate \> 30 breaths/min; plus 2. severe respiratory distress; or spo2 ≤ 88% on room air or pao2/fio2≤ 300 mm of hg, plus 3. radiological evidence of bilateral lung infiltrate, and or 4. systolic bp \< 90 mm of hg or diastolic bp \<60 mm of hg. and or 5. criteria 1 to 4 and or patient in ventilator support

inclusion criteria: 1. respiratory rate \> 30 breaths/min; plus 2. severe respiratory distress; or spo2 ≤ 88% on room air or pao2/fio2≤ 300 mm of hg, plus 3. radiological evidence of bilateral lung infiltrate, and or 4. systolic bp \< 90 mm of hg or diastolic bp \<60 mm of hg. and or 5. criteria 1 to 4 and or patient in ventilator support

inclusion criteria: respiratory rate > 30 breaths/min; plus severe respiratory distress; or spo2 ≤ 88% on room air or pao2/fio2≤ 300 mm of hg, plus radiological evidence of bilateral lung infiltrate, and or systolic bp < 90 mm of hg or diastolic bp <60 mm of hg. and or criteria 1 to 4 and or patient in ventilator support

inclusion criteria: respiratory rate > 30 breaths/min; plus severe respiratory distress; or spo2 ≤ 88% on room air or pao2/fio2≤ 300 mm of hg, plus radiological evidence of bilateral lung infiltrate, and or systolic bp < 90 mm of hg or diastolic bp <60 mm of hg. and or criteria 1 to 4 and or patient in ventilator support

inclusion criteria: 1. respiratory rate > 30 breaths/min; plus 2. severe respiratory distress; or spo2 ≤ 88% on room air or pao2/fio2≤ 300 mm of hg, plus 3. radiological evidence of bilateral lung infiltrate, and or 4. systolic bp < 90 mm of hg or diastolic bp <60 mm of hg. and or 5. criteria 1 to 4 and or patient in ventilator support

inclusion criteria: 1. respiratory rate > 30 breaths/min; plus 2. severe respiratory distress; or spo2 ≤ 88% on room air or pao2/fio2≤ 300 mm of hg, plus 3. radiological evidence of bilateral lung infiltrate, and or 4. systolic bp < 90 mm of hg or diastolic bp <60 mm of hg. and or 5. criteria 1 to 4 and or patient in ventilator support