inclusion criteria: * hospitalised * adults 18 year or older * moderately severe disease (news score ≤ 6) * sars-cov-2 positive nasopharyngeal swab * expected time of admission \> 48 hours * signed informed consent must be obtained and documented according to ich gcp, and national/local regulations.

inclusion criteria: * hospitalised * adults 18 year or older * moderately severe disease (news score ≤ 6) * sars-cov-2 positive nasopharyngeal swab * expected time of admission \> 48 hours * signed informed consent must be obtained and documented according to ich gcp, and national/local regulations.

inclusion criteria: - hospitalised - adults 18 year or older - moderately severe disease (news score ≤ 6) - sars-cov-2 positive nasopharyngeal swab - expected time of admission > 48 hours - signed informed consent must be obtained and documented according to ich gcp, and national/local regulations.

inclusion criteria: - hospitalised - adults 18 year or older - moderately severe disease (news score ≤ 6) - sars-cov-2 positive nasopharyngeal swab - expected time of admission > 48 hours - signed informed consent must be obtained and documented according to ich gcp, and national/local regulations.